Looking for tips to find icebergs - surveillance of haemolytic uraemic syndrome to detect outbreaks of Shiga toxin-producing E. coli infection - (Eurosurveillance)
February 28, 2008 – 8:22 pmhttp://www.eurosurveillance.org/edition/v13n09/080228_4.asp
To the Editor: In a recent article, De Schrijver et al. described an outbreak of Verocytotoxin-producing Escherichia coli, syn. Shiga toxin-producing E. coli (STEC), linked to the consumption of ice cream produced at a farm in the province of Antwerp, Belgium [1]. Interestingly, the outbreak was identified through the time-clustering of patients who had developed haemolytic uraemic syndrome (HUS) and from whom STEC O145 was isolated.
HUS a triad of acute renal injury, micro-angiopathic haemolytic anaemia and thrombocytopenia predominantly affects children. A subset of STEC-infected patients (circa 5-15% in patients infected with serotype O157:H7) develop HUS, and more than 80% of childhood HUS is attributable to STEC infection [2].
E. coli O157:H7 dominates STEC disease statistics in many countries. Routine detection of this serotype in stool, by use of sorbitol-MacConkey (SMAC) agar, is well-established, timely and inexpensive. Other (”non-O157:H7″) STEC serotypes cannot be identified on SMAC agar because these […]
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